DNA and the New Theory of Evolution

Dr. James Shapiro
University of Chicago

7pm Friday
February 8th, 2013

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James A.

University of Chicago

James Shapiro is Professor of Biochemistry & Molecular Biophysics, Committee on Genetics, Genomics & Systems Biology, in the Department of Biochemistry and Molecular Biology at The University of Chicago.

Ph.D. in Genetics, October, 1968, Corpus Christi College, Cambridge, England, 1964-1967. B.A. in English Literature, Harvard College, 1964, Magna cum laude, Phi Beta Kappa.

Editorial Boards: Journal of Bacteriology, 1986-1988 Enzyme and Microbial Technology, 1981-1988 Biotechnology series, 1981-1988 FEMS Microbiological Reviews, 1985-1991 Research in Microbiology, 1996-2002 Environmental Microbiology, 1998-

Professional Societies: American Society for Microbiology Society for General Microbiology Genetics Society of America Genetical Society American Society for Biochemistry and Molecular Biology Fellow, American Association for the Advancement of Science Fellow, American Academy of Microbiology.

AWARDS & HONORS Marshall Scholarship (1964-1966) Wellcome Research Training Scholarship (1966-1967) Jane Coffin Childs Memorial Fund for Cancer Research Postdoctoral Fellowship (1967-69) NIH Research Career Development Award (1976-1980) Darwin Prize, University of Edinburgh (1993) Fellow, American Academy of Microbiology (1993) Foundation for Microbiology Lecturer, American Society for Microbiology (1994-6) AAAS Fellow (1994) OBE (2001)

The first tenet of classical Darwinian evolution is now refuted.

Beneficial mutations are NOT random, DNA seems to be DESIGNED to change in order to adapt to environment pressure. Hereditary variation arises from the non-random action of built-in biochemical systems that mobilize DNA and carry out natural genetic engineering.

My current research deals with understanding how cells regulate the natural genetic engineering systems that produce DNA rearrangements and formulating a new conceptual basis for genome evolution consistent with molecular genetics. I also collaborate with colleagues who study multicellular pattern formation in bacterial colonies.